Lovastatin | 1692

A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids.

Lovastatin is a cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase, a rate limiting enzyme in cholesterol synthesis.

1692 | Lovastatin DataSheet

Alternate Name/Synonyms: Mevinolin; Mevacor; Monacolin K; 6-α-Methylcompactin; MK-803

Appearance: White solid

Formulation: N/A

CAS Number: 75330-75-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₃₆O₅

Molecular Weight: 404.54

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (25 mg/ml) or Ethanol (30 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A HMG-CoA inhibitor

MDL Number: MFCD00072164

PubChem CID: 53232

SMILES: CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C

InChi: InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChi Key: PCZOHLXUXFIOCF-BXMDZJJMSA-N