Description
A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids.
Lovastatin is a cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase, a rate limiting enzyme in cholesterol synthesis.
Alternate Name/Synonyms: Mevinolin; Mevacor; Monacolin K; 6-α-Methylcompactin; MK-803
Appearance: White solid
Formulation: N/A
CAS Number: 75330-75-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₃₆O₅
Molecular Weight: 404.54
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (25 mg/ml) or Ethanol (30 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A HMG-CoA inhibitor
MDL Number: MFCD00072164
PubChem CID: 53232
SMILES: CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
InChi: InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
InChi Key: PCZOHLXUXFIOCF-BXMDZJJMSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |