LPHN1 Polyclonal Antibody | BS65810

LPHN1 Polyclonal Antibody | BS65810 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR) . Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

Storage & Stability: Store at 4°C short term. Aliquot and store at -17°C long term. Avoid freeze-thaw cycles.

Specificity: LPHN1 Polyclonal Antibody detects endogenous levels of LPHN1 protein.

Molecular Weight: ~160 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Calcium independent alpha latrotoxin receptor 1; Calcium-independent alpha-latrotoxin receptor 1; CIRL-1; CIRL1; CL1; CLIBA; G protein-coupled receptor for alpha-Latrotoxin; KIAA0821; Latrophilin 1; Latrophilin-1; Latrophilin1; LEC2; Lectomedin 2; Lectomedin-2; LPHN 1; LPHN1; LPHN1_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human LPHN1:201-300/1474

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: