LRP5 Polyclonal Antibody | E-AB-12546

LRP5 Polyclonal Antibody | E-AB-12546 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: BMND1, EVR1, EVR4, HBM, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Low-density lipoprotein receptor-related protein 5, LR3, LRP-5, Lrp5, LRP5, LRP7, OPPG, OPS, OPTA1, Osteoporosis pseudoglioma syndrome, VBCH2

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells

Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human LRP5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A