Description
LRRC19 Polyclonal Antibody | E-AB-52280 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: FLJ21302, Leucine rich repeat containing 19, leucine rich repeat containing protein 19, Leucine-rich repeat-containing protein 19, LRC19, LRRC 19, LRRC19
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling, Signal transduction
Background: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
Concentration: 1.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human LRRC19
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 42 kDa
Molecular Weight(Observed): Refer to figures