LRRC26 Antibody | 7539

LRRC26 Antibody | 7539 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: LRRC26 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRRC26.
The immunogen is located within the last 50 amino acids of LRRC26.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB, IHC-P, IF

Application: LRRC26 antibody can be used for detection of LRRC26 by Western blot at 0.5 - 1 μg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: LRRC26 antibody is human specific.

Positive Control 1: Cat. No. 1312 - Human Prostate Tissue Lysate

Positive Control 2: Cat. No. 1205 - Jurkat Cell Lysate

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 37 kDa
Observed: 48 kDa

Validation: N/A

Isoform: N/A

Purification: LRRC26 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: LRRC26 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: LRRC26 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: LRRC26 Antibody: CAPC, bA350O14.10, CAPC, Leucine-rich repeat-containing protein 26, BK channel auxiliary gamma subunit LRRC26

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues (1) . LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis (2) . LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels (3) .