LSM14A Antibody (C-term) [APR04005G]

LSM14A Antibody (C-term) [APR04005G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This LSM14A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human LSM14A.

Cellular Localisation: Cytoplasm, P-body. Cytoplasm, cytoskeleton, spindle. Cytoplasm, Stress granule

Molecular Weight: 50530

Clone: Polyclonal

Gene Name: LSM14A {ECO:0000303|PubMed:26339800, ECO:0000312|HGNC:HGNC:24489}

Gene ID: 26065

Function: Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation (PubMed:16484376, PubMed:17074753, PubMed:29510985) . Acts as a repressor of mRNA translation (PubMed:29510985) . May play a role in mitotic spindle assembly (PubMed:26339800) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Protein LSM14 homolog A, Protein FAM61A, Protein SCD6 homolog, Putative alpha-synuclein-binding protein, AlphaSNBP, RNA-associated protein 55A, hRAP55, hRAP55A, LSM14A, C19orf13, FAM61A, RAP55, RAP55A