LTA4H Antibody | 18-672

LTA4H Antibody | 18-672 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 312-611 of human LTA4H (NP_000886.1) .

Research Area: Cancer, Immunology, Innate Immunity

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: HepG2

Positive Control 3: PC-3

Positive Control 4: SW620

Positive Control 5: BT-474

Positive Control 6: Ramos

Molecular Weight: Observed: 69kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: LTA4H, LTA4

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP) , a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD) . Several transcript variants encoding different isoforms have been found for this gene.