Description
Lucigenin is a chemiluminescent probe for the detection of superoxide in biological systems. It has been used for the generation of chemiluminescence in the presence of a reductant and oxygen. Lucigenin is also used as a fluorescent chloride-sensitive indicator, with fluorescence being quenched by chloride (excitation: 455 nm; emission: 505 nm). Lucigenin fluorescence is insensitive to phosphate, sulfate, and nitrate.
Lucigenin is a chemiluminescent probe for the detection of superoxide in biological systems. It has been used for the generation of chemiluminescence in the presence of a reductant and oxygen. Lucigenin is also used as a fluorescent chloride-sensitive indicator, with fluorescence being quenched by chloride (excitation: 455 nm; emission: 505 nm). Lucigenin fluorescence is insensitive to phosphate, sulfate, and nitrate.
Alternate Name/Synonyms: 9,9'-Bis(N-methylacridinium nitrate); N,N'-Dimethyl-9,9'-biacridinium dinitrate; L-6868; NSC-151912
Appearance: Yellow solid with orange tinge
Formulation: N/A
CAS Number: 2315-97-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₈H₂₂N₄O₆
Molecular Weight: 510.5
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A chemiluminescent probe for the detection of superoxide in biological systems
MDL Number: MFCD00011925
PubChem CID: 65099
SMILES: C[N+]1=C2C=CC=CC2=C(C3=CC=CC=C31)C4=C5C=CC=CC5=[N+](C6=CC=CC=C64)C.[N+](=O)([O-])[O-].[N+](=O)([O-])[O-]
InChi: InChI=1S/C28H22N2.2NO3/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28;2*2-1(3)4/h3-18H,1-2H3;;/q+2;2*-1
InChi Key: KNJDBYZZKAZQNG-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |