LXN Polyclonal Antibody | E-AB-10437

LXN Polyclonal Antibody | E-AB-10437 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ECI, Endogenous carboxypeptidase inhibitor, Latexin, Latexin protein, LXN, LXN, MUM, Protein MUM, TCI, Tissue carboxypeptidase inhibitor

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Immunology, Stem Cells, Tags and Cell Markers

Background: Latexin, also designated endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), belongs to the protease inhibitor I47 family of proteins. Latexin acts as a non-competitive, reversible inhibitor for metallocarboxypeptidases (MCPs), including CPA1, CPA2 and CPA4. It is a cytoplasmic protein that is highly expressed in heart, prostate, pancreas, ovary, kidney, brain and colon. Latexin consists of two topologically equivalent subdomains that bind to MCPs with low specificity, which gives it with the flexibility to inhibit all vertebrate A/B MCPs.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human LXN

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 26 kDa

Molecular Weight(Observed): N/A