LY-2940680 | 9604

LY-2940680 binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling pathway. Displays anticancer properties.

LY-2940680 binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling pathway. Displays anticancer properties.

9604 | LY-2940680 DataSheet

Alternate Name/Synonyms: 4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide; LY2940680; Taladegib

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1258861-20-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₂₄F₄N₆O

Molecular Weight: 512.5

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent Hedgehog (Hh) signaling pathway inhibitor

MDL Number: N/A

PubChem CID: 49848070

SMILES: CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F

InChi: InChI=1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3

InChi Key: SZBGQDXLNMELTB-UHFFFAOYSA-N