Description
LY-2940680 binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling pathway. Displays anticancer properties.
LY-2940680 binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling pathway. Displays anticancer properties.
Alternate Name/Synonyms: 4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide; LY2940680; Taladegib
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1258861-20-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₆H₂₄F₄N₆O
Molecular Weight: 512.5
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent Hedgehog (Hh) signaling pathway inhibitor
MDL Number: N/A
PubChem CID: 49848070
SMILES: CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F
InChi: InChI=1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3
InChi Key: SZBGQDXLNMELTB-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |