LY2608204 | 2824

LY2608204 is a potent activator of glucokinase (GK) with EC₅₀ of 42 nM. Potential antidiabetic agent to treat type 2 diabetes.

LY2608204 is a potent activator of glucokinase (GK) with EC₅₀ of 42 nM. Potential antidiabetic agent to treat type 2 diabetes.

2824 | LY2608204 DataSheet

Alternate Name/Synonyms: (1R,2S)-2-cyclohexyl-1-(4-(cyclopropylsulfonyl)phenyl)-N-(5-(2-(pyrrolidin-1-yl)ethylthio)thiazol-2-yl)cyclopropanecarboxamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1234703-40-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₃₇N₃O₃S₃

Molecular Weight: 559.81

Cell-Permeable?: yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>100 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent glucokinase (GK) activator

MDL Number: N/A

PubChem CID: 46832368

SMILES: C1CCC(CC1)C2CC2(C3=CC=C(C=C3)S(=O)(=O)C4CC4)C(=O)NC5=NC=C(S5)SCCN6CCCC6

InChi: InChI=1S/C28H37N3O3S3/c32-26(30-27-29-19-25(36-27)35-17-16-31-14-4-5-15-31)28(18-24(28)20-6-2-1-3-7-20)21-8-10-22(11-9-21)37(33,34)23-12-13-23/h8-11,19-20,23-24H,1-7,12-18H2,(H,29,30,32)/t24-,28-/m0/s1

InChi Key: QIIVJLHCZUTGSD-CUBQBAPOSA-N