LY315920 | 2666

LY315920 is a potent, and selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2) (IC₅₀ = 9± 1 nM). Potential anti-inflammatory agent.

LY315920 is a potent, and selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2) (IC₅₀ = 9± 1 nM). Potential anti-inflammatory agent.

2666 | LY315920 DataSheet

Alternate Name/Synonyms: [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate; Varespladib; S-5920

Appearance: Of-white to pale yellow solid

Formulation: N/A

CAS Number: 172732-68-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₀N₂O₅

Molecular Weight: 380.39

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent secretory PLA2 (sPLA2) inhibitor

MDL Number: N/A

PubChem CID: 155815

SMILES: CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OCC(=O)O)C(=O)C(=O)N

InChi: InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)

InChi Key: BHLXTPHDSZUFHR-UHFFFAOYSA-N