Description
LY315920 is a potent, and selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2) (IC₅₀ = 9± 1 nM). Potential anti-inflammatory agent.
LY315920 is a potent, and selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2) (IC₅₀ = 9± 1 nM). Potential anti-inflammatory agent.
Alternate Name/Synonyms: [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate; Varespladib; S-5920
Appearance: Of-white to pale yellow solid
Formulation: N/A
CAS Number: 172732-68-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₀N₂O₅
Molecular Weight: 380.39
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>50 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent secretory PLA2 (sPLA2) inhibitor
MDL Number: N/A
PubChem CID: 155815
SMILES: CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OCC(=O)O)C(=O)C(=O)N
InChi: InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)
InChi Key: BHLXTPHDSZUFHR-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |