LY96 Antibody (C-term) [APR17258G]

LY96 Antibody (C-term) [APR17258G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This LY96 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the C-terminal region of human LY96.

Cellular Localisation: Secreted, extracellular space. Secreted Note=Retained in the extracellular space at the cell surface by interaction with TLR4 (PubMed:10359581) .

Molecular Weight: 18546

Clone: Polyclonal

Gene Name: LY96

Gene ID: 23643

Function: Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869) . Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030) . Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581) . Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Lymphocyte antigen 96, Ly-96, ESOP-1, Protein MD-2, LY96, ESOP1, MD2