Lycorine hydrochloride | B3237

Lycorine is a naturally occurring alkaloid found in plants in the Amaryllidaceae family; it displays antifungal, anti-parasitic, and anticancer activities. Acts as a selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway

Lycorine is a naturally occurring alkaloid found in plants in the Amaryllidaceae family; it displays antifungal, anti-parasitic, and anticancer activities. Acts as a selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway

B3237 | Lycorine hydrochloride DataSheet

Alternate Name/Synonyms: (1S,17S,18S,19S)-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol;hydrochloride,Lycorine HCl

Appearance: Off-white solid

Formulation:

CAS Number: 2188-68-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₇NO₄.HCl

Molecular Weight: 323.77

Cell-Permeable?: True

Purity: ≥98%

Solubilities: >50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A biologically active alkaloid

MDL Number: MFCD00243111

PubChem CID: 164943

SMILES: C1CN2CC3=CC4=C(C=C3C5C2C1=CC(C5O)O)OCO4.Cl

InChi: InChI=1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1

InChi Key: VUVNTYCHKZBOMV-NVJKKXITSA-N