Description
Lycorine is a naturally occurring alkaloid found in plants in the Amaryllidaceae family; it displays antifungal, anti-parasitic, and anticancer activities. Acts as a selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway
Lycorine is a naturally occurring alkaloid found in plants in the Amaryllidaceae family; it displays antifungal, anti-parasitic, and anticancer activities. Acts as a selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway
B3237 | Lycorine hydrochloride DataSheet
Alternate Name/Synonyms: (1S,17S,18S,19S)-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol;hydrochloride,Lycorine HCl
Appearance: Off-white solid
Formulation:
CAS Number: 2188-68-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₇NO₄.HCl
Molecular Weight: 323.77
Cell-Permeable?: True
Purity: ≥98%
Solubilities: >50 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A biologically active alkaloid
MDL Number: MFCD00243111
PubChem CID: 164943
SMILES: C1CN2CC3=CC4=C(C=C3C5C2C1=CC(C5O)O)OCO4.Cl
InChi: InChI=1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1
InChi Key: VUVNTYCHKZBOMV-NVJKKXITSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |