LYPD6B Antibody (Center) (Ascites) [AMM22143G]

LYPD6B Antibody (Center) (Ascites) [AMM22143G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H, M

Specificity: This LYPD6B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the Central region of human LYPD6B.

Cellular Localisation: Cell membrane; Lipid-anchor, GPI- anchor

Molecular Weight: 20656

Clone: Monoclonal

Gene Name: LYPD6B

Gene ID: 130576

Function: Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3 (3) :beta- 4 (2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha- 3 (2) :alpha-5:beta-4 (2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.

Summary: N/A

Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:500~4000

Synonyms: Ly6/PLAUR domain-containing protein 6B, LYPD6B