LYRM1 Antibody | 5659

LYRM1 Antibody | 5659 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: LYRM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human LYRM1.
The immunogen is located within the first 50 amino acids of LYRM1.

Research Area: Obesity

Tested Application: E, WB, IHC-P, IF

Application: LYRM1 antibody can be used for detection of LYRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1304 - Human Liver Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: LYRM1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: LYRM1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: LYRM1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: LYRM1 Antibody: A211C6.1, LYR motif-containing protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: LYRM1 Antibody: LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.