M344 | 1607

An amide analog of Trichostatin A (Cat.# 1606-1) that potently Inhibits histone deacetylases (IC₅₀ = 40 nM for rat liver HDAC and IC₅₀ = 100 nM for maize HDAC). Induces differentiation and inhibits proliferation (~2 µM) of murine erythroleukemia cells.

M344 is an amide analog of Trichostatin A (Cat.# 1606-1) that potently Inhibits histone deacetylases (IC₅₀ = 40 nM for rat liver HDAC and IC₅₀ = 100 nM for maize HDAC).

1607 | M344 DataSheet

Alternate Name/Synonyms: 4-Dimethylamino-N-(6-hydroxycarbamoyl-hexyl)-benzamide

Appearance: White solid

Formulation: N/A

CAS Number: 251456-60-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₂₅N₃O₃

Molecular Weight: 307.39

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO ( 1mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A HDAC inhibitor

MDL Number: MFCD03453554

PubChem CID: 3994

SMILES: CN(C)C1=CC=C(C=C1)C(=O)NCCCCCCC(=O)NO

InChi: InChI=1S/C16H25N3O3/c1-19(2)14-10-8-13(9-11-14)16(21)17-12-6-4-3-5-7-15(20)18-22/h8-11,22H,3-7,12H2,1-2H3,(H,17,21)(H,18,20)

InChi Key: MXWDSZWTBOCWBK-UHFFFAOYSA-N