MAGEA1 (F293) polyclonal Antibody | BS1217

MAGEA1 (F293) polyclonal Antibody | BS1217 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC: 1:50~1:200

Background: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MAGE-1 (F293) polyclonal Antibody detects endogenous levels of MAGE-1 protein. This Antibody also detects endogenous levels of Tumor antigen MAGE-N.

Molecular Weight: ~ 34, 46 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen; MAGEA1; MAGE1; MAGE1A; Tumor antigen MAGE-N

Immunogen: Synthetic peptide, corresponding to amino acids 280-320 of Human MAGE-1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: