MAGI2 Antibody (C-term) [APR33074G]

MAGI2 Antibody (C-term) [APR33074G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M, Rat

Specificity: This MAGI2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1123-1156 amino acids from the C-terminal region of human MAGI2.

Cellular Localisation: Cytoplasm. Late endosome. Cell junction, synapse, synaptosome. Cell membrane; Peripheral membrane protein Note=Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation Membrane-associated in synaptosomes (By similarity) .

Molecular Weight: 158754

Clone: Polyclonal

Gene Name: MAGI2

Gene ID: 9863

Function: Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF) -induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.

Summary: Tissue Location: Specifically expressed in brain.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, Atrophin-1-interacting protein 1, AIP-1, Atrophin-1-interacting protein A, Membrane-associated guanylate kinase inverted 2, MAGI-2, MAGI2, ACVRINP1, AIP1, KIAA0705