Mambalgin-1 | 2421

Mambalgin-1 is a peptide toxin originally isolated from the venom of Black Mamba (Dendroaspis polylepis polylepis). Acts as an analgesic. Mambalgin-1 is able to abolish pain through inhibition of acid-sensing ion channels (ASICs) expressed either in central or peripheral neurons.

Mambalgin-1 is a peptide toxin originally isolated from the venom of Black Mamba (Dendroaspis polylepis polylepis). Acts as an analgesic. Mambalgin-1 is able to abolish pain through inhibition of acid-sensing ion channels (ASICs) expressed either in central or peripheral neurons.

2421 | Mambalgin-1 DataSheet

Alternate Name/Synonyms:

Appearance: Lyophilized solid

Formulation: N/A

CAS Number: N/A

Structure Available?: No

Peptide sequence: H-Leu- Lys- Cys- Tyr- Gln- His- Gly- Lys- Val- Val- Thr- Cys- His- Arg- Asp- Met- Lys- Phe- Cys- Tyr- His- Asn- Thr- Gly- Met- Pro- Phe- Arg- Asn- Leu- Lys- Leu- Ile- Leu- Gln- Gly- Cys- Ser- Ser- Ser- Cys- Ser- Glu- Thr- Glu- Asn- Asn- Lys- Cys- Cys- Ser- Thr- Asp- Arg- Cys- Asn- Lys-OH (disulfide bonds between Cys3 - Cys19, Cys12 - Cys37, Cys41 - Cys49 and Cys50 - Cys55 )

Salt Form: TFA

Molecular Formula: C₂₇₂H₄₂₉N₈₅O₈₄S₁₀

Molecular Weight: 6554.61

Cell-Permeable?: No

Purity: ≥90% by HPLC

Solubilities: H₂O

Handling: Protect from light and air

Country of Origin: USA

Tag Line: An analgesic

MDL Number: N/A

PubChem CID: N/A

SMILES: N/A

InChi: N/A

InChi Key: N/A