Description
Mambalgin-1 is a peptide toxin originally isolated from the venom of Black Mamba (Dendroaspis polylepis polylepis). Acts as an analgesic. Mambalgin-1 is able to abolish pain through inhibition of acid-sensing ion channels (ASICs) expressed either in central or peripheral neurons.
Mambalgin-1 is a peptide toxin originally isolated from the venom of Black Mamba (Dendroaspis polylepis polylepis). Acts as an analgesic. Mambalgin-1 is able to abolish pain through inhibition of acid-sensing ion channels (ASICs) expressed either in central or peripheral neurons.
Alternate Name/Synonyms:
Appearance: Lyophilized solid
Formulation: N/A
CAS Number: N/A
Structure Available?: No
Peptide sequence: H-Leu- Lys- Cys- Tyr- Gln- His- Gly- Lys- Val- Val- Thr- Cys- His- Arg- Asp- Met- Lys- Phe- Cys- Tyr- His- Asn- Thr- Gly- Met- Pro- Phe- Arg- Asn- Leu- Lys- Leu- Ile- Leu- Gln- Gly- Cys- Ser- Ser- Ser- Cys- Ser- Glu- Thr- Glu- Asn- Asn- Lys- Cys- Cys- Ser- Thr- Asp- Arg- Cys- Asn- Lys-OH (disulfide bonds between Cys3 - Cys19, Cys12 - Cys37, Cys41 - Cys49 and Cys50 - Cys55 )
Salt Form: TFA
Molecular Formula: C₂₇₂H₄₂₉N₈₅O₈₄S₁₀
Molecular Weight: 6554.61
Cell-Permeable?: No
Purity: ≥90% by HPLC
Solubilities: H₂O
Handling: Protect from light and air
Country of Origin: USA
Tag Line: An analgesic
MDL Number: N/A
PubChem CID: N/A
SMILES: N/A
InChi: N/A
InChi Key: N/A
Additional Information
Storage Condition: |
-20 ̊C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |