MAP2K5 Polyclonal Antibody | E-AB-10512

MAP2K5 Polyclonal Antibody | E-AB-10512 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Dual specificity mitogen activated protein kinase kinase 5, Dual specificity mitogen-activated protein kinase kinase 5, EC 2.7.12.2, HsT17454, MAP kinase kinase 5, MAP kinase kinase MEK5b, MAP2K5, MAPK/ERK kinase 5, MAPKK 5, MAPKK5, MEK 5, mitogen-activated protein kinase kinase 5, MKK5, MP2K5, PRKMK5, Protein kinase, mitogen-activated, kinase 5, SAPKK5, SKK5

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Signal Transduction

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human MAP2K5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A