MAP3K13 (LZK) Antibody (C-term) [AMM22159G]

MAP3K13 (LZK) Antibody (C-term) [AMM22159G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: Purified His-tagged MAP3K13 protein fragment was used to produced this monoclonal antibody.

Cellular Localisation: Cytoplasm. Membrane; Peripheral membrane protein

Molecular Weight: 108296

Clone: Monoclonal

Gene Name: MAP3K13 (HGNC:6852)

Gene ID: 9175

Function: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB- containing complex that phosphorylates inhibitors of NF-kappa-B.

Summary: Tissue Location: Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: IF, WB

Dilution: WB--1:500

Synonyms: Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK, MAP3K13 (HGNC:6852)