MAP4K1 (Y381) Antibody [APR33663G]

MAP4K1 (Y381) Antibody [APR33663G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MAP4K1 (Y381) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human MAP4K1 (Y381) .

Cellular Localisation: N/A

Molecular Weight: 91296

Clone: Polyclonal

Gene Name: MAP4K1

Gene ID: 11184

Function: Serine/threonine-protein kinase, which may play a role in the response to environmental stress (PubMed:24362026) . Appears to act upstream of the JUN N-terminal pathway (PubMed:8824585) . May play a role in hematopoietic lineage decisions and growth regulation (PubMed:8824585, PubMed:24362026) . Able to autophosphorylate (PubMed:8824585) . Together with CLNK, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity) .

Summary: Tissue Location: Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Mitogen-activated protein kinase kinase kinase kinase 1, 2.7.11.1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEKKK 1, MAP4K1, HPK1