Description
MAP4K3 Polyclonal Antibody | E-AB-14391 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: GLK, MEKKK3, MEKKK 3, MAPKKKK3, RAB8IPL1
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Signal Transduction
Background: This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human MAP4K3
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 101 kDa
Molecular Weight(Observed): N/A