MATER polyclonal Antibody | BS90826

MATER polyclonal Antibody | BS90826 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, mouse

Application: ICC

Application Range: ICC:1:200

Background: NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals. Conserved oocyte-specific expression of NLRP5 is consistent among many mammalian species. As a member of the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress beyond the first embryonic cell divisions. NLRP5 also localizes to the nuclear envelope and mitochondria in germinal vesicle oocytes, suggesting a possible role in mitochondrial function.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MATER polyclonal Antibody detects endogenous levels of MATER protein.

Molecular Weight: 134 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MATER, NALP5, CLR19.8, MATER, Mater protein homolog, Maternal antigen that embryos require, NACHT, leucine rich repeat and PYD containing 5, NACHT, LRR and PYD domains-containing protein 5, NALP5, NLR family, pyrin domain containing 5, NLRP5, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5, PAN11, PYPAF8,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: