MATN2 Antibody | 5105

MATN2 Antibody | 5105 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: MATN2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human MATN2.
The immunogen is located within amino acids 820 - 870 of MATN2.

Research Area: Homeostasis

Tested Application: E, WB

Application: MATN2 antibody can be used for detection of MATN2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1282 - 3T3 (NIH) Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 102 kDa
Observed: 105 kDa

Validation: N/A

Isoform: N/A

Purification: MATN2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: MATN2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: MATN2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: MATN2 Antibody: Matrilin-2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: MATN2 Antibody: Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.