MBOAT7 Antibody (Center) [APR17331G]

MBOAT7 Antibody (Center) [APR17331G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MBOAT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human MBOAT7.

Cellular Localisation: Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localized in specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria.

Molecular Weight: 52765

Clone: Polyclonal

Gene Name: MBOAT7 (HGNC:15505)

Gene ID: 79143

Function: Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1- acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1, 2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (PubMed:18772128, PubMed:18094042) . Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell (PubMed:18772128, PubMed:18094042) . In liver, participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation (PubMed:32253259) .

Summary: Tissue Location: Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000 WB--1:2000

Synonyms: Lysophospholipid acyltransferase 7, LPLAT 7, 231-, 1-acylglycerophosphatidylinositol O-acyltransferase, 231n4, Bladder and breast carcinoma-overexpressed gene 1 protein, Leukocyte receptor cluster member 4, Lysophosphatidylinositol acyltransferase, LPIAT, Lyso-PI acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 7, O-acyltransferase domain-containing protein 7, h-mboa-7, MBOAT7, BB1, LENG4, OACT7