MC2R Antibody | 18-905

MC2R Antibody | 18-905 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of human MC2R

Research Area: Cancer, Neuroscience, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: Raji

Positive Control 2: Mouse kidney

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 37kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: MC2R, melanocortin 2 receptor (adrenocorticotropic hormone) , ACTHR, MGC125798, ACTH receptor, MC2 receptor, adrenocorticotropic hormone receptor, corticotropin receptor, melanocortin 2 receptor

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC) . MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.