MC3R polyclonal Antibody | BS7740

MC3R polyclonal Antibody | BS7740 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:2000

Background: The melanocortin family comprises the α-, β- and γ- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MC3R polyclonal Antibody detects endogenous levels of MC3R protein.

Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BMIQ9; MC3; MC3 R; MC3-R; Mc3r; MC3R_HUMAN; melanocortin 3 receptor; Melanocortin receptor 3; OB20; Obesity quantitative trait locus; OQTL;

Immunogen: Recombinant full length Human MC3R.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: