MCB613 | B2268

MCB-613 is a small-molecule steroid coactivators SRC-1, SRC-2, and SRC-3 that has been used to disrupt cancer cell homeostatic dependence on SRCs. MCB-613 can super-stimulate SRCs’ transcriptional activity and increase SRCs’ interactions with other coactivators and markedly induce ER stress coupled to the generation of reactive oxygen species (ROS)

MCB-613 is a small-molecule steroid coactivators SRC-1, SRC-2, and SRC-3 that has been used to disrupt cancer cell homeostatic dependence on SRCs. MCB-613 can super-stimulate SRCs’ transcriptional activity and increase SRCs’ interactions with other coactivators and markedly induce ER stress coupled to the generation of reactive oxygen species (ROS)

B2268 | MCB613 DataSheet

Alternate Name/Synonyms: 4-ethyl-2,6-bis(3-pyridinylmethylene)-cyclohexanone

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1162656-22-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₀N₂O

Molecular Weight: 304.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A small-molecule steroid coactivators SRC-1, SRC-2, and SRC-3

MDL Number: N/A

PubChem CID: 2175947

SMILES: CCC1CC(=CC2=CN=CC=C2)C(=O)C(=CC3=CN=CC=C3)C1

InChi: InChI=1S/C20H20N2O/c1-2-15-9-18(11-16-5-3-7-21-13-16)20(23)19(10-15)12-17-6-4-8-22-14-17/h3-8,11-15H,2,9-10H2,1H3/b18-11+,19-12+

InChi Key: MMBSCBVEHMETSA-GDAWTGGTSA-N