MCM2 Polyclonal Antibody | E-AB-10452

MCM2 Polyclonal Antibody | E-AB-10452 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: BM28, CCNL 1, CCNL1, CDC like 1, cdc19, CDCL 1, CDCL1, Cell devision cycle like 1, Cyclin like 1, D3S3194, DNA replication licensing factor MCM2, KIAA0030, MCM 2, MCM2, MCM2 minichromosome maintenance deficient 2 mitotin, MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae), MCM2 minichromosome maintenance deficient 2, mitotin, MCM2, MGC10606, Minichromosome maintenance complex component 2, Minichromosome maintenance deficient 2 (mitotin), Minichromosome maintenance deficient 2 mitotin, Minichromosome maintenance protein 2, Minichromosome maintenance protein 2 homolog, Mitotin, Nuclear protein BM28, OTTHUMP00000216047, OTTHUMP00000216050

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex witHuman, MouseCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human MCM2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 102 kDa

Molecular Weight(Observed): N/A