MCP1 Polyclonal Antibody | BS65630

MCP1 Polyclonal Antibody | BS65630 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse, Rat

Application: WB,

Application Range: WB=1:500-2000

Background: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1 ( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MCP1 Polyclonal Antibody detects endogenous levels of MCP1 protein.

Molecular Weight: 11 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MCP-1; monocyte chemotactic protein 1; CCL 2; CCL2; Chemokine C C motif ligand 2; Chemokine CC Motif Ligand 2; GDCF 2; GDCF 2 HC11; GDCF2; HC11; HSMCR30; JE; MCAF; MCP 1; MGC9434; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; SCYA2; Small inducible cytokine A2; Small inducible cytokine subfamily A Cys Cys member 2; SMC CF; SMCCF.

Immunogen: KLH conjugated synthetic peptide derived from human MCP1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: