MCSF polyclonal Antibody | BS90833

MCSF polyclonal Antibody | BS90833 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC ICC IP

Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:100

Background: The macrophage colony-stimulating factor (M-CSF), also designated CSF-1, was originally discovered in serum, urine and other biological fluids as a factor that can stimulate the formation of macrophage colonies from bone marrow hematopoietic progenitor cells. M-CSF is a homodimeric cytokine that is produced by fibroblasts, epithelial cells, bone marrow stromal cells, osteoblasts, keratinocytes, macrophages, T cells and B cells. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages. M-CSF exerts its pleiotropic effects by binding to a single type of high affinity cell surface receptor that is encoded by the c-Fms proto-oncogene.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MCSF polyclonal Antibody detects endogenous levels of MCSF protein.

Molecular Weight: 60 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CSF-1, M-CSF, MCSF, CSF1, Colony stimulating factor 1 (macrophage), Colony stimulating factor 1, Colony stimulating factor macrophage specific, CSF 1, CSF-1, CSF1, CSF1, Csfm, Lanimostim, M CSF, M-CSF, Macrophage Colony Stimulating Factor 1, Macrophage colony stimulating factor, MCSF, MGC31930, Processed macrophage colony-stimulating factor 1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: