Description
MDFI Polyclonal Antibody | E-AB-18801 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: I MF, I mfa, Inhibitor of MyoD family a, Mdfi, MDFI, MyoD family inhibitor, Myogenic repressor I-mf, OTTHUMP00000016375, OTTHUMP00000016376, OTTHUMP00000196103, OTTHUMP00000196414, OTTHUMP00000196415
Application: WB, IHC, ELISA
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling, Developmental Biology
Background: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.MDFI (MyoD Family Inhibitor) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding. An important paralog of this gene is MDFIC.
Concentration: 0.96 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human MDFI
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 25 kDa
Molecular Weight(Observed): Refer to figures