MDH2 polyclonal Antibody | BS8109

MDH2 polyclonal Antibody | BS8109 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200

Background: MDH2 (malate dehydrogenase, NAD mitochondrial), also known as MDH, MOR1 or M-MDH, is a 338 amino acid that belongs to the LDH/MDH superfamily. MDH2 localizes to the mitochondria and may play a critical role in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. MDH2 utilizes the NAD/NADH cofactor system in the citric acid cycle to catalyze the reversible oxidation of malate to oxaloacetate. Oxaloacetate is involved in many important metabolic pathways including amino acid synthesis, gluconeogenesis and facilitation of the exchange of metabolites between cytoplasm and subcellular organelles.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MDH2 polyclonal Antibody detects endogenous levels of MDH2 protein.

Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Malate dehydrogenase; mitochondrial; MDH2

Immunogen: Recombinant full length Human MDH2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: