MDK-7933 | B2119

MDK-7933 is a potent HDAC8 inhibitor with an IC₅₀ of 27.2 nM in cancer cell lines. MDK-7933 displays antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5).

MDK-7933 is a potent HDAC8 inhibitor with an IC₅₀ of 27.2 nM in cancer cell lines. MDK-7933 displays antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5).

B2119 | MDK-7933 DataSheet

Alternate Name/Synonyms: (E)-N-hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide; HDAC8-IN-1

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1417997-93-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₁₉NO₃

Molecular Weight: 345.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent HDAC8 inhibitor

MDL Number: N/A

PubChem CID: N/A

SMILES: ONC(/C=C/C1=CC=C(C=C1C2=CC=C(C=C2)C3=CC=CC=C3)OC)=O

InChi: nChI=1S/C22H19NO3/c1-26-20-13-11-19(12-14-22(24)23-25)21(15-20)18-9-7-17(8-10-18)16-5-3-2-4-6-16/h2-15,25H,1H3,(H,23,24)/b14-12+

InChi Key: ASHPRZYGCOMVHO-WYMLVPIESA-N