Additional Information
Size: |
100 µg |
Target: |
MDM2 |
Conjugate: |
PerCP |
Research Area: |
Cancer, Cell Cycle, p53 Pathway, Cell Signaling, Epigenetics and Nuclear Signaling, Cancer, Tumor Biomarkers, Oncoproteins |
Alternative Name: |
Double minute 2 protein Antibody, Hdm2 Antibody, MTBP Antibody, Mouse Double Minute 2 Antibody, HDMX Antibody, ACTFS Antibody, p53 Binding Protein Mdm2 Antibody, Ubiquitin protein ligase E3 Mdm2 Antibody, Mdm2 p53 E3 ubiquitin protein ligase homolog |
Category: |
Antibodies |
Product Type: |
Polyclonal |
Immunogen: |
Synthetic peptide from the mid-protein of Human MDM2 (aa. 100-200) |
Immunogen Species: |
Human |
Applications: |
WB, IHC |
Isotype: |
NA |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:1000); IHC (1:50); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide |
Concentration: |
1 mg/ml |
Specificity: |
Detects ~50 kDa. ~50 kDa band is isoform 2 or 3. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
A 1:1000 dilution of SPC-778 was sufficient for detection of MDM2 in 15 µg of mouse, rat Brain cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. |
Cellular Localization: |
Nucleus, Nucleoplasm, Cytoplasm, Nucleus, Nucleolus |
Accession Number: |
NP_001138811.1 |
Gene ID: |
4193 |
Swiss-Prot: |
Q00987 |
Tissue Specificity: |
Ubiquitous. Isoform Mdm2-A, isoform Mdm2-B, isoform Mdm2-C, isoform Mdm2-D, isoform Mdm2-E, isoform Mdm2-F and isoform Mdm2-G are observed in a range of cancers but absent in normal tissues. |
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