MECOM Polyclonal Antibody | E-AB-19826

MECOM Polyclonal Antibody | E-AB-19826 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Ecotropic Virus Integration Site 1 Protein Homolog, MDS1 And EVI1 Complex Locus Protein, PR Domain 3, EVI1, MDS1, MDS1 And EVI1 Complex Locus Protein EVI1, MDS1 And EVI1 Complex Locus Protein MDS1, Ecotropic Viral Integration Site 1, Myelodysplasia Syndrome 1 Protein, Zinc Finger Protein Evi1, Oncogene EVI1, AML1-EVI-1, MDS1-EVI1, RUSAT2, KMT8E, PRDM3

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Concentration: 1.68 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human MECOM

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A