MED30 polyclonal Antibody | BS60175

MED30 polyclonal Antibody | BS60175 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Med30 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. The mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, and is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Found in the nucleus, Med30 is expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MED30 polyclonal Antibody detects endogenous levels of MED30 protein.

Molecular Weight: ~ 19 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Mediator of RNA polymerase II transcription subunit 30; Mediator complex subunit 30; TRAP/Mediator complex component TRAP25; Thyroid hormone receptor-associated protein 6; Thyroid hormone receptor-associated protein complex 25 kDa component; Trap25; THRAP6; TRAP25

Immunogen: A synthetic peptide corresponding to residues in Human MED30.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: