MEKK1 Antibody (C-term) [APR32521G]

MEKK1 Antibody (C-term) [APR32521G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MEKK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1145-1176 amino acids from the C-terminal region of human MEKK1.

Cellular Localisation: N/A

Molecular Weight: 164470

Clone: Polyclonal

Gene Name: MAP3K1

Gene ID: 4214

Function: Component of a protein kinase signal transduction cascade (PubMed:9808624) . Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624) . May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173) . Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Mitogen-activated protein kinase kinase kinase 1, MAPK/ERK kinase kinase 1, MEK kinase 1, MEKK 1, MAP3K1, MAPKKK1, MEKK, MEKK1