Description
Menadione is an inhibitor of indoleamine2,3-dioxygenase (IDO) (IC₅₀ ~ 1 µM). It induces apoptosis via elevation of peroxide radical levels. Cytotoxic in various cell lines.
Menadione is an inhibitor of indoleamine2,3-dioxygenase (IDO) (IC₅₀ ~ 1 µM). It induces apoptosis via elevation of peroxide radical levels. Cytotoxic in various cell lines.
Alternate Name/Synonyms: 2-Methyl-1,4-naphthoquinone, Vitamin K3
Appearance: Off-white to yellow solid
Formulation: N/A
CAS Number: 58-27-5
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₁H₈O₂
Molecular Weight: 172.18
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (1 mg/ml) or 96% EtOH (~ 15 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An IDO inhibitor
MDL Number: MFCD00001681
PubChem CID: 4055
SMILES: CC1=CC(=O)C2=CC=CC=C2C1=O
InChi: InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
InChi Key: MJVAVZPDRWSRRC-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |