Description
MERTK Antibody | 19-665 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 840-999 of human MERTK (NP_006334.2) .
Research Area: Cell Cycle, Neuroscience, Signal Transduction
Tested Application: WB, IF
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: 22Rv1
Positive Control 2: Mouse liver
Positive Control 3: Mouse kidney
Positive Control 4: Mouse lung
Positive Control 5: Mouse spleen
Positive Control 6: Rat liver
Molecular Weight: Observed: 160kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: MERTK, c-mer proto-oncogene tyrosine kinase, MER, MGC133349, c-mer, MER receptor tyrosine kinase, STK kinase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .