MESP2 polyclonal Antibody | BS60610

MESP2 polyclonal Antibody | BS60610 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: MESP2 (mesoderm posterior 2 homolog), also known as SCDO2 or bHLHc6 (class C basic helix-loop-helix protein 6), is a 397 amino acid protein that contains one basic helix-loop-helix (bHLH) domain, a motif that mediates protein dimerization and can bind to the E-box sequence of DNA. Localized to the nucleus, MESP2 functions as a transcription factor that, via its bHLH domain, participates in the epithelialization and the development of the cardiac and somitic mesoderm. MESP2 is involved in somitogenesis and Notch pathways and is encoded by a gene that maps to human chromosome 15q26.1. Defects in the MESP2 gene are the cause of an autosomal recessive disorder known as spondylocostal dysostosis type 2 (SCDO2) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MESP2 polyclonal Antibody detects endogenous levels of MESP2 protein.

Molecular Weight: ~ 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Mesoderm posterior protein 2; Class C basic helix-loop-helix protein 6; bHLHc6; MESP2; BHLHC6; SCDO2

Immunogen: A synthetic peptide corresponding to residues in Human MESP2

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: