Methazolamide | B3259

Methazolamide is a potent carbonic anhydrase (CA) inhibitor (IC50 = 130 nM) with anti-glaucoma, anti-diabetic, and potential anti-neoplastic activity. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma.

Methazolamide is a potent carbonic anhydrase (CA) inhibitor (IC50 = 130 nM) with anti-glaucoma, anti-diabetic, and potential anti-neoplastic activity. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma.

B3259 | Methazolamide DataSheet

Alternate Name/Synonyms: N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-acetamide

Appearance: White to off-white solid

Formulation:

CAS Number: 554-57-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₈N₄O₃S₂

Molecular Weight: 263.27

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A carbonic anhydrase inhibitor

MDL Number: MFCD00083416

PubChem CID: 4100

SMILES: CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C

InChi: InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)

InChi Key: FLOSMHQXBMRNHR-UHFFFAOYSA-N