26
Metoclopramide Hydrochloride | B3112
- SKU:
- 26-B3112-GEN
- Availability:
- Usually shipped in 5 working days
Description
Metoclopramide is a 5-hydroxytryptamine (serotonin) 5-HT3 receptor antagonist and dopamine D2 receptor antagonist. Metoclopramide inhibits 5-HT3 receptor and Dopamine D2 receptor binding affinity with IC₅₀ values of 308 nM and 483 nM, in rat brain cortical membranes and synaptic membranes respectively. It is used as a stimulant of upper gastrointestinal motility and as an antiemetic agent.
Metoclopramide is a 5-hydroxytryptamine (serotonin) 5-HT3 receptor antagonist and dopamine D2 receptor antagonist. Metoclopramide inhibits 5-HT3 receptor and Dopamine D2 receptor binding affinity with IC₅₀ values of 308 nM and 483 nM, in rat brain cortical membranes and synaptic membranes respectively. It is used as a stimulant of upper gastrointestinal motility and as an antiemetic agent.
B3112 | Metoclopramide Hydrochloride DataSheet
Alternate Name/Synonyms: 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride; 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide hydrochloride; Maxolon
Appearance: White to off-white crystalline powder
Formulation:
CAS Number: 7232-21-5
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₁₄H₂₃Cl₂N₃O₂
Molecular Weight: 336.26
Cell-Permeable?: True
Purity: ≥ 98%
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A 5-HT3 and dopamine D2 receptor antagonist
MDL Number: MFCD00058011
PubChem CID: 23659
SMILES: CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.Cl
InChi: InChI=1S/C14H22ClN3O2.ClH/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H
InChi Key: RVFUNJWWXKCWNS-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |